Author: Kathlynn Brown
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Tumor-specific intracellular delivery: peptide-guided transport of a catalytic toxin
Here we optimize our lead peptide by a series of chemical modifications including truncations, N-terminal capping, and changes in valency.
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Introduction of plasmid encoding for rare tRNAs reduces amplification bias in phage display biopanning
Here we present a method that reduces amplification bias by addition of a plasmid that encodes six low abundance tRNAs into K91 Escherichia coli.
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Identification of a Novel Lysosomal Trafficking Peptide Using Phage Display Biopanning Coupled with Endocytic Selection Pressure
We performed phage display biopanning on cancer cells that are treated with selective inhibitors of a given mechanism of endocytosis.