Author: Peter Karp
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Representations of Metabolic Knowledge
We survey representations used for several metabolic databases, including EcoCyc, and reach the following conclusions..
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A Qualitative Biochemistry and its Application to the Regulation of the Tryptophan Operon
This article is concerned with the general question of how to represent biological knowledge in computers such that it may be used in multiple problem solving tasks.
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The Grasper-CL Graph Management System
Grasper-CL [5] is a COMMON LISP system for manipulating and displaying graphs, and for building graph-based user interfaces for application programs.
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The Design Space of Frame Knowledge Representation Systems
This paper surveys the FRS design space in search of design principles for FRSs.
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A knowledge base of the chemical compounds of intermediary metabolism
This paper describes a publicly available knowledge base of the chemical compounds involved in intermediary metabolism.
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Artificial intelligence methods for theory representation and hypothesis formation
This article describes artificial intelligence methods for representing theories in molecular biology, and for improving the predictive power of these theories using experimental data.
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Hypothesis Formation as Design
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An Analysis of the Distinction Between Deep and Shallow Expert Systems
This paper analyzes the relationship between the techniques used to build expert systems and the behaviors they exhibit to show that there is not sufficient evidence to link the behavioral shortcomings of first-generation expert systems to the shallow methods of representation and inference they employ.
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Coordinating the Use of Qualitative and Quantitative Knowledge in Declarative Device Modeling
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The Pony Express Network Mail Delivery System and the MM-32 Mail Manager
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Computer-Assisted Three-Dimensional and Two-Dimensional Reconstructions of Autoradiographic Images of the Cerebral Cortex
This report describes a computer system that generates reconstructions of film autoradiographs of the cerebral cortex.
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Computer-Assisted Analysis of Tomographic Images of the Brain
A computer system for the analysis of computed tomography and positron emission tomography scans of the brain is described.