Biomedical sciences publications
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Women with Dysmenorrhoea Are Hypersensitive to Experimentally Induced Forearm Ischaemia During Painful Menstruation and During the Pain-Free Follicular Phase
We investigated whether women with dysmenorrhoea, compared with controls, have increased sensitivity to experimentally induced deep-tissue muscle ischaemia in a body area distant from that of referred menstrual pain.
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Bioprotective Carnitinoids: Lipoic Acid, Butyrate, and Mitochondria-Targeting to Treat Radiation Injury: Mitochondrial Drugs Come of Age
There is an urgent need for effective medicines to protect against and treat the harmful biological effects of radiation . Potential strategies herein include mitochondrial and epigenetic-driven methods using lipoic…
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Insomnia in Women Approaching Menopause: Beyond Perception
We aimed to quantify sleep disturbance and the underlying contribution of objective hot flashes in 72 women who had, compared to those who had not, developed clinical insomnia in association…
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Clock Genes X Stress X Reward Interactions in Alcohol and Substance Use Disorders
The aim of the present review is to summarize findings linking clock genes, stress, and alcohol and substance abuse, and to propose potential underlying neurobiological mechanisms.
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Addiction, Freedom, and Responsibility
In his article supporting an evolutionary perspective of free will, John Banja (2015) argues that addicts are responsible for their addictive behaviors because they could engage in practices that would diminish…
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Brain Development in Heavy-Drinking Adolescents
The authors measured within-subject changes in regional brain morphometry over longer intervals and in larger samples of adolescents than previously reported and assessed differences between adolescents who remained nondrinkers and…
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K12 CS Teaching Methods Courses
CS teacher development has become a major effort for the SIGCSE community in part due to NSF's CS10K efforts and expanding CSTA involvement. However there are few examples of university…
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Characterization of Batracylin-Induced Renal and Bladder Toxicity in Rats
To further investigate batracylin’s mechanism of toxicity, studies were conducted in Fischer 344 rats. Once daily oral administration of 16 or 32 mg/kg batracylin to rats for 4 days caused…
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Cardiac Autonomic Function During Sleep: Effects of Alcohol Dependence and Evidence of Partial Recovery with Abstinence
Chronic alcoholism is associated with the development of cardiac and peripheral autonomic nervous system (ANS) pathology.
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Biomarkers of Response to Smoking Cessation Pharmacotherapies: Progress to Date
Recent research has begun to determine biomarkers (such as genotype, nicotine and metabolite levels, and brain imaging findings) that may have utility in predicting smoking cessation.
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Classification of Lexical Stress Using Spectral and Prosodic Features for Computer-assisted Language Learning Systems
We present a system for detection of lexical stress in English words spoken by English learners. This system was designed to be part of the EduSpeak® computer-assisted language learning (CALL)…
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Activation of alpha2-Adrenergic Receptor by (R,R’)-4′-Methoxy-1-Naphthylfenoterol Inhibits Proliferation and Motility of Melanoma Cells
Taken together, these results identified β2-AR as a novel potential target for melanoma management, and (R,R')-MNF as an efficient trigger of anti-tumorigenic cAMP/PKA-dependent signaling in β2-AR-expressing lesions.