Biomedical sciences publications
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Dynamic Responses of Selective Brain White Matter Fiber Tracts to Binge Alcohol and Recovery in the Rat
To determine the dynamics of white matter vulnerability to excessive alcohol consumption, diffusion tensor imaging (DTI) was used in an animal model of alcohol exposure.
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Pharmacokinetics and Metabolism of 4R-Cembranoid
The purpose of this study was to examine the metabolism and pharmacokinetics of 4R as part of its preclinical development as a neuroprotective drug.
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Targeting N-Glycan Cryptic Sugar Moieties for Broad-Spectrum Virus Neutralization: Progress in Identifying Conserved Molecular Targets in Viruses of Distinct Phylogenetic Origins
In this study, we characterized two broadly HIV-neutralizing agents, human monoclonal antibody 2G12 and Galanthus nivalis lectin (GNA), for their viral targeting activities.
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K12 CS Teaching Methods Courses
BOF attendees are asked to bring materials from their classes and be ready to discuss multiple viewpoints about topics, pedagogical strategies and readings from a rich history of research in…
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Preclinical Studies on the Pharmacokinetics, Safety, and Toxicology of Oxfendazole: Toward First in Human Studies
A 2-week study in rats identified target organs of oxfendazole toxicity to be bone marrow, epididymis, liver, spleen, testis, and thymus.
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Formulation Approaches to Improving the Delivery of an Antiviral Drug with Activity against Seasonal Flu
The main objective of the present study was to develop formulations of noscapine hydrochloride hydrate with enhanced solubility and bioavailability using co-solvent- and cyclodextrin-based approaches.
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Emergence of terpene cyclization in Artemisia annua
Here we report the first discovery of an epistatic network of residues that controls the onset of terpene cyclization in Artemisia annua.
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The Acute Effects of Alcohol on Sleep Electroencephalogram Power Spectra in Late Adolescence
Background Alcohol’s effect on sleep electroencephalogram (EEG) power spectra during late adolescence is of interest given that this age group shows both dramatic increases in alcohol consumption and major sleep-related…
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Sleep in Women: A Review
This article reviews the literature on the characteristics of, and contributing factors to, subjectively and objectively measured sleep during the menstrual cycle, pregnancy, and post-partum period, as well as the…
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Controlling Haematophagous Insects: The Quality-of-Life Scenario
This chapter highlights the financial and psychological impact of haematophagous insects in urban environments, using bedbugs as an example. The utility of strategies for vector control in the management of…
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Advances in Nanotechnology and Microfluidics for Human Papillomavirus Diagnostics
Here, we review the existing assays and platforms employed for HPV diagnosis, and highlight recent advances in nanotechnology and microfluidics that potentially enable new approaches for HPV diagnosis.
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Modular Three-component Delivery System Facilitates HLA Class I Antigen Presentation and CD8(+) T-Cell Activation against Tumors
Here we present a nanoparticle delivery system that facilitates presentation of an immunogenic measles antigen specifically in cancer cells.