Biomedical sciences publications
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In Vivo Diffusion Tensor Imaging Evidence for Reversible White Matter Microstructural Integrity Disruption: Effects of Abstinence in Rat and Man
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Design and Synthesis of Molecular Probes for the Determination of the Target of the Anthelmintic Drug Praziquantel
In this Letter, we report an efficient protocol for the small-scale separation of enantiomers of 2 (hydrolyzed PZQ) using supercritical fluid chromatography (SFC).
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Sobriety Length and Lifetime Alcohol Consumption Modulate Brain Response to Emotional Faces and Alcohol Pictures in Abstinent Alcoholics
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Trajectory of Visuospatial Learning Compromise in Alcoholism with and without HIV Infection: 10-Year Longitudinal Study
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Dynamic Metabolic Imaging of Hyperpolarized [2-C-13]Pyruvate Using Spiral Chemical Shift Imaging with Alternating Spectral Band Excitation
This study introduces a sequence for three-dimensional CSI of [2-(13) C]pyruvate using spectrally selective excitation of limited frequency bands containing a subset of metabolites. Dynamic CSI data were acquired alternately…
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The Acute and Chronic Effects of Alcohol Consumption on Sleep Architecture in College Aged Students
This study examined the effect of alcohol on sleep architecture in women and men aged 18 to 21 years and whether previously reported sleep architecture effects may have been as…
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Association between Personality Traits and DSM-IV Diagnosis of Insomnia in Peri- and Postmenopausal Women
The aim of this study was to determine the role of personality factors in the development of DSM-IV insomnia coincident with perimenopause.
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Evidence for the Role of EPHX Gene Variants in Anorexia Nervosa
To identify genetic variants associated with AN, we pursued a series of sequencing and genotyping studies focusing on the coding regions and upstream sequence of 152 candidate genes in a…
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Regional Manifold Learning for Disease Classification
We use the regional manifolds as low-dimensional descriptors of high-dimensional morphological image features, which are then fed into a classifier to identify regions affected by disease.
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Effect of Bitopertin, a Glycine Reuptake Inhibitor, on Negative Symptoms of Schizophrenia: A Randomized, Double-Blind, Proof-of-Concept Study
Our objective is to determine the efficacy and safety of bitopertin (RG1678), a glycine reuptake inhibitor, in patients with schizophrenia and predominant negative symptoms who were stable while taking an…
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Evidence of Recovery in Cortico-Cardiac Activity During Sleep in Recently Detoxified Alcoholics
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Sleep EEG Evidence of Early Brain Recovery with Abstinence in Long-Term Alcoholics