Biomedical sciences publications
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Use of CFU-GM Assay to Determine Radiation-Induced Hematotoxicity in Mice
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Influence of Inhibitory Serotonergic Inputs to Orexin/Hypocretin Neurons on the Diurnal Rhythm of Sleep and Wakefulness
Inhibitory serotonergic input likely contributes to wakefulness bouts, affecting the diurnal rhythm of sleep and wakefulness.
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A Multicenter Evaluation of Oral Pressure Therapy for the Treatment of Obstructive Sleep Apnea
We aimed to evaluate the impact of a novel noninvasive oral pressure therapy (OPT) (Winx®, ApniCure) system on polysomnographic measures of sleep-disordered breathing, sleep architecture, and sleep stability in obstructive…
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Environmental Levels of Bisphenol-A Can Expand Numbers of Mammary Stem Cells and Potentially Increase Breast Cancer Risk
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Nicotine Reduces Established Levodopa-Induced Dyskinesias in a Monkey Model of Parkinson’s Disease
The goal of this study was to determine whether the duration of nicotine administration affects its ability to reduce LIDs in levodopa-primed and levadopa-naíve monkeys and also to test whether…
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Association of CD28 and CTLA-4 Gene Polymorphisms with Aggressive Periodontitis in Brazilians
Our hypothesis is that polymorphisms in genes that code for these molecules may be associated with periodontitis. The aim of the study was to investigate the association between +17 (T/C) CD28 and…
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Microglial Beclin 1regulates Retromer Trafficking and Phagocytosis and Is Impaired in Alzheimer’s Disease
Here we show that the autophagy protein beclin 1 is required for efficient phagocytosis in vitro and in mouse brains. Interestingly, microglia isolated from human Alzheimer’s disease (AD) brains show significantly…
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A Zero CO2-Emitting Process for Transportation Fuels from Coal and Natural Gas Resources
Simultaneous steam reforming of natural gas and conversion of coal to syngas was achieved in a gas-blown, electrically heated, entrained-flow gasifier. Conversions > 95% for both coal and natural gas…
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Outcomes from a Patient-Centered Residential Treatment Plan for Tobacco Dependence
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Dose-Dependent Efficacy and Safety Toxicology of Hydroxypyridinonate Actinide Decorporation Agents in Rodents: Towards a Safe and Effective Human Dosing Regimen
The results of these studies add to the growing body of evidence that both decorporation agents have remarkable decorporation efficacy properties and promising safety toxicology profiles.
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Estradiol Modulates Recovery of Rem Sleep in a Time-of-Day-Dependent Manner
In this study, we asked whether the effect of ovarian hormones on sleep is mediated via circadian or homeostatic regulatory mechanisms.
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Fiber Tract-Driven Topographical Mapping (FTTM) Reveals Microstructural Relevance for Interhemispheric Visuomotor Function in the Aging Brain
We present a novel approach – DTI-based fiber tract-driven topographical mapping – to map and measure the influence of age on the integrity of interhemispheric fibers and challenge their selective…