Biomedical sciences publications
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Sheet-Like White Matter Fiber Tracts: Representation, Clustering, and Quantitative Analysis
We introduce an automated and probabilistic method for subject-specific segmentation of sheet-like fiber tracts.
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Sleep EEG, the Clearest Window Through Which to View Adolescent Brain Development
The paper by Tarokh and colleagues in this issue of SLEEP highlights how longitudinal sleep EEG data is arguably the optimal functional measure of these structural brain changes.
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Utility of a Brief Instrument for Assessing Alcohol Tolerance in Social Drinkers
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A Comparison of in Vivo Neurochemical Sequelae of Binge Alcohol Exposure in Wild-Type Wistar, Alcohol Preferring, and Alcohol Nonpreferring Rats
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A High-Throughput Fluorescence Polarization Assay for Inhibitors of Gyrase B
The assay performed with an average Z′ factor of 0.80 and was able to identify GyrB inhibitors from a screening library.
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Relationship Between Circulating Platelet Counts and Ductus Arteriosus Patency After Indomethacin Treatment
In contrast to the evidence in mice, low circulating platelet counts do not affect permanent ductus closure (or ductus reopening) in human preterm infants.
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Functional and Anatomical Remapping of Corticocerebellar Loops in Alcoholism
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Independent Contributions of Cortical Gray Matter, Aging, Sex and Alcoholism to K-Complex Amplitude Evoked During Sleep
The amplitude of the N550 component derived from the averaged evoked K-complex decreases with normal aging and with alcoholism. The study was designed to determine whether these declines are related…
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Recommendations for the Validation of Flow Cytometric Testing During Drug Development: I Instrumentation
This paper presents a consensus methodological approach that the authors have used successfully to ensure data integrity in flow cytometric studies conducted during drug development.
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Functional and Structural Connectivity and Executive Control in Chronic Alcoholism: a Combined DTI and fMRI Study
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Neurological assessments after treatment with the antimalarial beta-arteether in neonatal and adult rats
This study shows that repeated treatment with clinically relevant doses of βAE causes motor deficits associated with brainstem damage in rodents and suggests that repeated treatment with βAE in children…
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Partial Occupancy of the Glycine Transporter Type 1 in Monkey By Rg1678 Leads to Efficacy in a Model of Prefrontal Cortical Function