Biomedical sciences publications
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MicroRNA Expression Differentiates Histology and Predicts Survival of Lung Cancer
We investigated whether microRNA (miR) expression profiles can differentiate histologic subtypes and predict survival for non–small cell lung cancer.
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Shewanella knowledgebase: integration of the experimental data and computational predictions suggests a biological role for transcription of intergenic regions
The Shewanella knowledgebase was established in 2005 to provide a framework for integrated genome-based studies on Shewanella ecophysiology.
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Integrated Genomic Analysis Identifies Clinically Relevant Subtypes of Glioblastoma Characterized By Abnormalities in PDGFRA, IDH1, EGFR, and NF1
We provide a framework that unifies transcriptomic and genomic dimensions for GBM molecular stratification with important implications for future studies.
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Binge Ethanol Treatment Is Insufficient to Elevate Cytokine Levels Measured in Rat Blood, Liver, and Brain
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Disrupted Frontocerebellar Networks in Alcoholics Revealed By Resting State Functional Connectivity Imaging
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Synthesis and Tissue Distribution Studies of Acyloxyalkyl Prodrug Derivative of an Anti-HBV Dinucleotide
The preferential distribution of the dinucleotide 1 and its prodrug 2 into liver may be attributed to the presence of nucleoside phosphorothioate backbone because phosphorothioate oligonucleotides also reveal a similar…
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The Metal-Responsive Transcription Factor-1 Protein Is Elevated in Human Tumors
In the present study, we investigated MTF-1 protein expression in human tissues by specific immunostaining of both normal and tumor tissue samples.
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Disruption of Bottom-Up Processes in Alcoholics: Examination with Visuoperceptual Testing and Quantitative Fiber Tracking
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DEGAS: de novo discovery of dysregulated pathways in human diseases
While a pathway is usually defined as a set of genes known to share a specific function, pathway boundaries are frequently difficult to assign, and methods that rely on such…
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Diffusion MR Imaging in Neuropsychiatry and Aging
This chapter provides a review of diffusion imaging findings in normal aging and a sampling of neuropsychiatric diseases, and adds to a growing list of such overviews
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Focus on the Brain: HIV Infection and Alcoholism Comorbidity Effects on Brain Structure and Function
Both HIV infection and alcohol abuse have negative effects on the brain, with some unique to each condition and others shared by both conditions. Investigators have used magnetic resonance imaging…
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Folate Receptor Targeted Nanophosphors for Enhanced Tumor Radiotherapy
Here we present a folic acid (FA) conjugated nanophosphor (NP) intended to enhance the therapeutic effect of radiotherapy by augmenting the production of reactive oxygen species with simultaneous photodynamic therapy…