Biomedical sciences publications
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Episodic Memory in Detoxified Alcoholics: Contribution of Grey Matter Microstructure Alteration
These findings support the hypothesis that regional microstructural but no macrostructural alteration of the brain might be responsible, at least in part, for episodic memory deficits in alcohol dependence.
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Diclofenac Potassium Restores Objective and Subjective Measures of Sleep Quality in Women with Primary Dysmenorrhea
We determined the effectiveness of diclofenac potassium, compared to placebo, in alleviating nighttime pain and restoring sleep architecture in women with primary dysmenorrhea.
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Visualizing Implanted Tumors in Mice with Magnetic Resonance Imaging Using Magnetotactic Bacteria
Magnetotactic bacteria can produce positive magnetic resonance imaging contrast and colonize mouse tumor xenografts, providing a potential tool for improved magnetic resonance imaging visualization in preclinical and translational studies to…
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MRI Estimates of Brain Iron Concentration in Normal Aging: Comparison of Field-Dependent (Fdri) and Phase (Swi) Methods
The results showed that both methods detected high globus pallidus iron concentration regardless of age and significantly greater iron in putamen with advancing age.
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Recruitment of CD8(+) T Cells Expressing Granzyme A is Associated with Lesion Progression in Human Cutaneous Leishmaniasis
Our goal was to characterize the immunological kinetics associated with the progression of an infection establishing CL, comparing the cellular composition, cytokines and granzyme expression between lesions of patients with…
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Biology of Charged Particles
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Cellular and Genetic Mechanisms Involved in the Generation of Protective and Pathogenic Immune Responses in Human Chagas Disease
Perhaps one of the most intriguing aspects of human Chagas disease is the complex network of events that underlie the generation of protective versus pathogenic immune responses during the chronic…
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A Novel Peroxisome Proliferator-Activated Receptor Delta Antagonist, SR13904, has Anti-Proliferative Activity in Human Cancer Cells
The peroxisome proliferator-activated receptor delta (PPARδ) is a ligand-activated, nuclear receptor transcription factor that has a documented role in glucose and lipid homeostasis.
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A Systems Biology Network Model for Genetic Association Studies of Nicotine Addiction and Treatment
We discuss several applications of our ontology: to support interdisciplinary research by graphically representing a complex scientific theory, to facilitate meta-analysis across different studies, to highlight potential interactions, and to…
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Working and Episodic Memory in HIV Infection, Alcoholism, and Their Comorbidity: Baseline and 1-Year Follow-Up Examinations
Selective memory deficits occur in individuals with human immunodeficiency virus (HIV) infection and those with chronic alcoholism, but the potential compounded effect of these conditions is seldom considered, despite the…
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The Impact of Alcoholism on Sleep Evoked Delta Frequency Responses
The KC incidence and amplitude were negatively impacted in alcoholic men and women with exacerbation of the normal aging effects, particularly over frontal scalp regions.
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Dopamine and Opioid Gene Variants Are Associated with Increased Smoking Reward and Reinforcement Owing to Negative Mood
We explored associations of gene variants in the dopamine, opioid, and serotonin pathways with smoking reward (‘liking’) and reinforcement (latency to first puff and total puffs) as a function of negative mood…