Biomedical sciences publications
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Multiple Distinct Risk Loci for Nicotine Dependence Identified By Dense Coverage of the Complete Family of Nicotinic Receptor Subunit (CHRN) Genes
We analyzed 226 SNPs covering the complete family of 16 CHRN genes, which encode the nicotinic acetylcholine receptor (nAChR) subunits, in a sample of 1,050 nicotine-dependent cases and 879 non-dependent controls of…
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Self-Reported Sleep Habits in Middle School Girls: the Girls’ Middle School Longitudinal Sleep Survey
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Choline Acetyltransferase Expression During Spontaneous Sleep-Wake Bouts Over 24H
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Enhanced Alpha-Synuclein Expression in Human Neurodegenerative Diseases: Pathogenetic and Therapeutic Implications
Here we discuss the possibility that other mechanisms of alpha-synuclein elevation contribute to the pathogenesis of idiopathic, sporadic Parkinson's disease and other human synucleinopathies.
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Expression of Plasticity-Related Genes During Eszopiclone-Induced Sleep
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Nociceptin/Orphanin FQ Antagonists Ameliorate the Disease Pathogenesis During Inflammatory Bowel Disease
We evaluated the therapeutic potential of N/OFQ antagonists in C57Bl/6 mice in an IBD model after disease induction by treatment for 5 days with DSS, and subsequent observation of the…
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Therapeutic Efficacy of a Melatonin Agonist, Ramelteon, and a Benzodiazepine, Triazolam, in a Mouse Genetic Model of Advanced Sleep Phase Syndrome
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Pharmacokinetics and Immunogenicity Assays for a Human Monoclonal Antibody Mixture Specific for Botulinum Neurotoxin A
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Identification of “Sleep Genes” from Natural and Pharmacologically Induced Sleep Studies
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Processing of Emotional and Alcohol Stimuli in Chronic Alcoholism
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Subject-Matched Templates for Spatial Normalization
Here, we introduce the concept of subject-matched templates. Rather than using a single template for the entire population, a different template is used for every subject, with the template matched…
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The Impact of Alcoholism in Men and Women on Polysomnography and Sleep EEG