Biomedical sciences publications
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Telephone-Based Tobacco-Cessation Treatment Re-Enrollment Among Diverse Groups
This study aimed to determine the rates of quitline re-enrollment and to compare the responses of people of varying racial/ethnic identities to invitations utilizing different communication strategies.
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L-Selectin-Deficient SJL and C57Bl/6 Mice Are Not Resistant to Experimental Autoimmune Encephalomyelitis
L-selectin has been suggested to play a role in the pathogenesis of experimental autoimmune encephalomyelitis (EAE), an animal model of multiple sclerosis. Here we demonstrate that L-selectin–/– SJL mice are susceptible…
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Neuroinflammation as a Neurotoxic Mechanism in Alcoholism: Commentaryon “Increased Mcp-1 and Microglia in Various Regions of Human Alcoholic Brain”
Neuropathological studies of chronic alcoholism indicate that loss of neurons is selective to frontal cortex (Courville, 1955, Harper and Kril, 1990) with little evidence for widespread cell loss (Harper, 1998,…
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Systematic Biological Prioritization After a Genome-Wide Association Study: an Application to Nicotine Dependence
We introduce a method for systematically prioritizing single nucleotide polymorphisms (SNPs) for further study after a GWAS. The method combines evidence across multiple domains including statistical evidence of genotype–phenotype correlation,…
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Diffusion Tensor Tractography in Mesencephalic Bundles: Relation to Mental Flexibility in Detoxified Alcohol-Dependent Subjects
Components of the corticocerebellar circuit and the midbrain individually play a central role in addictive processes and have been associated with altered volumes and impairment of cognitive flexibility in alcohol-dependent…
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Nociceptin Attenuates Methamphetamine Abstinence-Induced Withdrawal-Like Behavior in Planarians
In the present study, we tested the hypothesis that abrupt discontinuation of methamphetamine would also cause withdrawal-like behavior in planarians and that the withdrawal-like behavior would be prevented by nociceptin,…
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Gamma-Aminobutyric Acid Receptor Genes and Nicotine Dependence: Evidence for Association from a Case-Control Study
We found evidence for association between four SNPs in GABRA4, two SNPs in GABRA2 and one SNP in GABRE with nicotine dependence.
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Callosal Microstructural Degradation Affects Self-And Externally-Directed Visual Conjunction Search in Aging and Alcoholism
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Image-Guided Surgical Navigation in Implant-Based Auricular Reconstruction
In cases where surgical reconstruction is not an option, placement of osseo-integrated implants for an auricular prosthesis can be done in 1 or 2 stages in a relatively short period…
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Nicotinic Acetylcholine Receptor Beta 2 Subunit Gene Implicated in a Systems-Based Candidate Gene Study of Smoking Cessation
We performed a systems-based candidate gene study of 1295 single nucleotide polymorphisms (SNPs) in 58 genes within the neuronal nicotinic receptor and dopamine systems to investigate their role in smoking…
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Perceived Sleep Quality and Sleepiness in South African University Students
Nine hundred and eighty-six undergraduate students completed a questionnaire about their sleep and lifestyle habits over the previous month, and their fatigue-related driving history.
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Long-Term Alcohol Exposure By Vapor Chamber Alters MRS Detectable Metabolites in Rat Striatum