Biomedical sciences publications
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In vivo Identification of Novel STAT5 Target Genes
To better characterize the differential contribution of STAT5A and STAT5B in gene regulation, we performed single or double knockdown of STAT5A and STAT5B using small interfering RNA. Subsequent gene expression…
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American Institute of Ultrasound in Medicine Consensus Report on Potential Bioeffects of Diagnostic Ultrasound: Executive Summary
The following summary is not meant as a substitute for the detailed examination of issues presented in each of the articles but rather as a means to facilitate further study…
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Fetal Thermal Effects of Diagnostic Ultrasound
Available evidence, experimental or epidemiologic, is insufficient to conclude that there is a causal relationship between obstetric diagnostic ultrasound exposure and obvious adverse thermal effects to the fetus.
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Children of Persons with Alzheimer Disease: What Does the Future Hold?
Children of persons with Alzheimer disease (AD), as a group, face an increased risk of developing AD.
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Sleep and Menstrual-Related Disorders
There are few studies of sleep in menstrual-related disorders. Preliminary evidence indicates subtle differences in sleep and circadian regulation in women with severe premenstrual syndrome, and increased subjective sleepiness in…
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Metallothionein Induction By Hypoxia Involves Cooperative Interactions Between Metal-Responsive Transcription Factor-1 and Hypoxia-Inducible Transcription Factor-1 Alpha
Here, we provide evidence that the protumorigenic hypoxia-inducible transcription factor-1α (HIF-1α) is essential for induction of MT-1 by hypoxia, but not zinc.
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Cortical Processing of Respiratory Afferent Stimuli During Sleep in Children with the Obstructive Sleep Apnea Syndrome
Cortical processing of respiratory afferent information can be tested by measuring respiratory-related evoked potentials (RREPs). We hypothesized that children with OSAS have blunted RREP responses compared to normal children during…
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The SRI24 Multi-Channel Brain Atlas: Construction and Applications
We present a new standard atlas of the human brain based on magnetic resonance images. The atlas was generated using unbiased population registration from high-resolution images obtained by multichannel-coil acquisition…
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Effect of Chitosans and Other Excipientson the Permeation of Ketotifen, FITC-Dextran, and Rhodamine 123 Through Caco-2 Cells
Ketotifen, FITC-labeled dextran, and Rhodamine 123 permeation was evaluated across Caco-2 cells grown on permeable inserts in the presence of chitosan, N,O-carboxymethyl chitosan (NOCC), Carbopol 934P, Polysorbate 80, and Disodium…
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Fast Parallel Spiral Chemical Shift Imaging at 3T Using Iterative Sense Reconstruction
Spiral chemical shift imaging (CSI) is a fast CSI technique that speeds up the data acquisition in comparison to conventional phase-encoded CSI by sampling the data while oscillating gradients are…
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Genes Implicated in Serotonergic and Dopaminergic Functioning Predict BMI Categories
This study addressed the hypothesis that variation in genes associated with dopamine function, serotonin function (SLC6A4, and regulation of monoamine levels (MAOA) may be predictive of BMI categories in young…
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Evaluation of Matrix Metalloproteinases in Atherosclerosis Using a Novel Noninvasive Imaging Approach
This study evaluated the ability of the novel gadolinium-based MRI contrast agent P947 to target MMPs in atherosclerotic plaques.