Biomedical sciences publications
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Heart Rate Variability During Sleep in Women with Severe Premenstrual Syndrome
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Inspiratory Contrast for in Vivo Optical Imaging
We demonstrate the use of inspired oxygen and carbon dioxide as a possible route to increase contrast in optical imaging of cancerous tissue.
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The Impact of Smoking Cessation on Sleep
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Evoked Delta Activity During Sleep in Alcoholism
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Fe-Radiation-Induced Alterations in Circulating Leukocyte Populations in the Apoe Mouse Atherosclerosis Model Are Temporary
We irradiated ApoE mice with 56Fe focused to the aorta and carotids to determine how irradiation of the thymus with 56Fe affects circulating lymphocyte number, and ultimately to determine the…
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Genetics of Nicotine Dependence and Pharmacotherapy
Despite significant strides in the understanding of the relative contribution of genetic and environmental factors to nicotine dependence and treatment, emergent challenges necessitate interdisciplinary coordinated effort for effective problem solving
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Effect of Resveratrol on 17 Beta-Estradiol Sulfation By Human Hepatic and Jejunal S9 and Recombinant Sulfotransferase 1E1
Abstract The purpose of this study was to investigate the sulfation of resveratrol (3,5,4′-trihydroxystilbene) and its potential to exhibit drug-drug interactions via sulfation. The possible interaction of resveratrol with 17β-estradiol…
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Frontal Callosal Integrity Predicts Cognitive Interference Compromise in Hiv-Infected Individuals Comorbid for Alcoholism
Diffusion tensor imaging was used to study the combined effects of HIV-infection and alcoholism (ALC) on corpus callosum (CC) integrity in relation to processes of attentional allocation and conflict resolution…
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Volume Reconstruction By Inverse Interpolation: Application to Interleaved MR Motion Correction
We introduce in this work a novel algorithm for volume reconstruction from data acquired on an irregular grid, e.g., from multiple co-registered images.
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Differential Expression of Clock-Related Genes in the Cerebral Cortex of Inbred Mouse Strains in Response to Sleep Deprivation
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Selective 5HT2A and 5HT6 Receptor Antagonists Promote Sleep in Rats
Serotonin (5-HT) has long been implicated in the control of sleep and wakefulness. This study evaluated the hypnotic efficacy of the 5-HT6 antagonist RO4368554 (RO) and the 5-HT2A receptor antagonist MDL100907 (MDL)…
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Preclinical Development of Neuropeptide Therapeutics and Diagnostics