Bioinformatics publications

The chief contributions of the paper are a minimized representation for biochemical pathways called the predecessor list, and inference procedures for converting the predecessor list into a pathway-graph representation that…

This article describes challenges and opportunities for addressing computational problems in the metabolism with techniques from knowledge representation, planning, integration of heterogeneous databases, qualitative reasoning, knowledge acquisition, and machine learning.

This paper presents algorithms for drawing metabolic pathways by dynamically querying the underlying knowledge base.

We survey representations used for several metabolic databases, including EcoCyc, and reach the following conclusions..

This article is concerned with the general question of how to represent biological knowledge in computers such that it may be used in multiple problem solving tasks.

Grasper-CL [5] is a COMMON LISP system for manipulating and displaying graphs, and for building graph-based user interfaces for application programs.

This paper surveys the FRS design space in search of design principles for FRSs.

This paper describes a publicly available knowledge base of the chemical compounds involved in intermediary metabolism.

This article describes artificial intelligence methods for representing theories in molecular biology, and for improving the predictive power of these theories using experimental data.

This paper analyzes the relationship between the techniques used to build expert systems and the behaviors they exhibit to show that there is not sufficient evidence to link the behavioral…