Biomedical sciences publications
-
Virally-induced expression of GABAA receptor δ subunits following their pathological loss reveals their role in regulating GABAA receptor assembly
Abstract Decreased expression of the δ subunit of the GABAA receptor (GABAAR) has been found in the dentate gyrus in several animal models of epilepsy and other disorders with increased…
-
Serum Biomarkers Reveal Long-term Cardiac Injury in Isoproterenol-treated African Green Monkeys
In this study, we have used filter-aided sample preparation (FASP) and tandem mass tag (TMT) labeling to investigate serum protein alterations in isoproterenol-treated African green monkeys.
-
Safety and Pharmacokinetic of Single Dose Novel Oral Androgen 11β-Methyl-19-Nortestosterone-17β-dodecylcarbonate in Men
The active drug 11β-MNT has androgenic and progestational activity, rapidly suppresses serum testosterone, and is a promising candidate for an effective once-daily oral male hormonal contraceptive.
-
How the COVID‐19 Pandemic Has Changed Our Lives: A Study of Psychological Correlates Across 59 Countries
This study examined the impact of the COVID-19 pandemic and subsequent social restrictions or quarantines on the mental health of the global adult population.
-
Effects of forehead cooling and supportive care on menopause-related sleep difficulties, hot flashes and menopausal symptoms: A pilot study
This pilot study explored the efficacy of a novel forehead cooling device for perceived sleep difficulties and hot flashes in menopausal-age women.
-
A standardized framework for testing the performance of sleep-tracking technology: Step-by-step guidelines and open-source code
Sleep-tracking devices are increasingly used in both research and clinical settings, providing new opportunities for large-scale data collection.
-
Stress, Sleep, and Autonomic Function in Healthy Adolescent Girls and Boys: Findings from the NCANDA Study
We investigated sex differences in the effect of stress on sleep and ANS activity in adolescents, using the first night in the laboratory as an experimental sleep-related stressor.
-
Impact of evening alcohol consumption on nocturnal autonomic and cardiovascular function in adult men and women: A dose–response laboratory investigation
Study Objectives: To investigate the dose-dependent impact of moderate alcohol intake on sleep-related cardiovascular (CV) function, in adult men and women.
-
Sparse epistatic patterns in the evolution of terpene synthases
We explore sequence determinants of enzyme activity and specificity in a major enzyme family of terpene synthases.
-
The Falling Asleep Process in Adolescents
The objective is to investigate the pre-sleep psychophysiological state and the arousal deactivation process across the sleep onset (SO) transition in adolescents.
-
The use of immersive virtual reality and slow breathing to enhance relaxation and sleep in adolescents
We evaluate the efficacy of a novel intervention based on virtual reality (VR) and slow breathing to promote bedtime relaxation and facilitate sleep in high-school adolescents.
-
Rigorous performance evaluation (previously, “validation”) for informed use of new technologies for sleep health measurement
This special article describes the rationale and priorities of an interdisciplinary effort for rigorous, standardized, and rapid performance evaluation of new sleep and sleep disorders related technologies of all kinds,…