Biomedical sciences publications
-
Total Exposure Study Analysis Consortium: A Cross-Sectional Study of Tobacco Exposures
The Total Exposure Study was designed to estimate levels of biomarkers of tobacco-specific and non-specific exposure and of potential harm in U.S. adult current cigarette smokers and tobacco product non-users.
-
Animal Paradigms to Assess Cognition with Translation to Humans
This chapter focuses on some promising translational cognitive paradigms for use in rodents, non-human primates, and humans.
-
Cognitive Demands During Quiet Standing Elicit Truncal Tremor in Two Frequency Bands: Differential Relations to Tissue Integrity of Corticospinal Tracts and Cortical Targets
Given the complexity of sensorimotor integration invoked to maintain upright posture, the integrity of supratentorial brain structures may also contribute to quiet standing and consequently be vulnerable to interference from…
-
Effect of the rs1051730-rs16969968 variant and smoking cessation treatment: a meta-analysis
Objective- To assess if the allelic variations of rs16969968/rs1051730 in the CHRNA5-CHRNA3-CHRNB4 gene cluster are associated with smoking cessation after nicotine replacement therapy (NRT).
-
Brain Pathways to Recovery from Alcohol Dependence
The purpose of this meeting is to provide fundamental insights on brain mechanisms that contribute to the recovery from alcohol dependence. Ultimately, it is to promote studies in understanding neurobiological…
-
Menstrual Cycle-Related Variation in Physiological Sleep in Women in the Early Menopausal Transition
The objective of the study was to assess the impact of menstrual cycle phase on the polysomnogram and electroencephalographic (EEG) features of sleep in midlife women.
-
In Vitro Metabolism and Stability of the Actinide Chelating Agent 3,4,3-Li(1,2-HOPO)
The preclinical characterization of this highly promising ligand comprised the evaluation of its in vitro properties, including microsomal, plasma, and gastrointestinal fluid stability, cytochrome P450 inhibition, plasma protein binding, and…
-
Anti-Mesothelin Nanobodies for Both Conventional and Nanoparticle-Based Biomedical Applications
Mesothelin is a cancer biomarker that is a target for nanotechnology-based diagnostic, therapeutic, and prognostic applications.
-
Higher Usual Alcohol Consumption Was Associated with a Lower 41-Y Mortality Risk from Coronary Artery Disease in Men Independent of Genetic and Common Environmental Factors: The Prospective NHLBI Twin Study
We evaluated whether alcohol consumption was prospectively associated with CAD mortality risk independent of familial factors.
-
Drug Metabolizing Enzyme and Transporter Gene Variation, Nicotine Metabolism, Prospective Abstinence, and Cigarette Consumption
We searched for drug metabolizing enzyme and transporter (DMET) gene variation associated with the NMR and prospective abstinence in 2,946 participants of laboratory studies of nicotine metabolism and of clinical…
-
Thalamic Structures and Associated Cognitive Functions: Relations with Age and Aging
This review presents studies that assess the relations between age and aging and the structure, function, and connectivity of the thalamus and associated neural networks and focuses on their relations…
-
Evidence for a Role for alpha6 nAChRs in L-Dopa-Induced Dyskinesias Using Parkinsonian alpha6 nAChR Gain-of-Function Mice
Here we investigate the role of α6β2* nAChRs, a subtype selectively present in the nigrostriatal pathway, using α6 nAChR subunit null mutant (α6(-/-)) mice.