Biomedical sciences publications

This chapter outlines the evidence for acute and chronic alcohol effects on sleep architecture and sleep electroencephalogram, evidence for tolerance with repeated administration, and possible underlying neurochemical mechanisms for alcohol's…

This review will summarize the current state of knowledge regarding HERV-K and cancer and attempt to outline the potential mechanisms by which HERV-K could be involved in the onset and…

We investigated cardiac vagal and sympathetic activity in 13 young primary insomniacs and 14 good sleepers during nocturnal sleep.

We have used NMR spectroscopy to characterize an oligonucleotide stem loop structure based on the pre-element of an oncogenic microRNA, miR-21.

In this paper, we consider the roles in a biology textbook, adapt a definition of roles based on upper ontologies, and relate it to the corresponding notions in linguistics and…

Our study aimed to investigate haemodynamic and behavioural responses during emotional stimulation in narco-cataplexy.

We investigated the association between CHRNA5-A3-B4 and smoking abstinence. The rs2056527(A) allele was associated with lower abstinence with active pharmacotherapy, or with nicotine gum alone but not significantly with bupropion.

We have developed preliminary laboratory data for formation of volatile aldehydes produced by oxidatation of amino acids found in ELF exposed to HOCl. Formation of HOCl, via oxidation of chloride…

In this process, doxcycline was oxidized to the N-oxide using m-CPBA. The hydrochloride salt of the tertiary N-oxide was treated with Fe(0)/FeCl3 catalyst yielding the N-demethylated product.

Zanamivir (Relenza™) and oseltamivir (Tamiflu(®)) are two antiviral drugs currently recommended by the CDC for treating influenza. Both are examples of the successful application of structure-based drug design strategies.