Biomedical sciences publications

In this work, the applicability of a novel imaging agent, [1,4-(13)C]-diethylsuccinate, for hyperpolarized (13)C metabolic imaging of the TCA cycle was explored.

We propose a new method for deformable registration of pre-operative and post-recurrence brain MR scans of glioma patients. To address this challenging task, our method, called PORTR, explicitly accounts for…

In the present study, the regulation of MMP-2 activation by α1(IV)NC1 was evaluated. α1β1-integrin which is required for inhibition of angiogenesis is not playing a role in cellular invasion and inhibition of…

We report an improved enantioselective synthesis of herboxidiene and the first report of its biologically active totally synthetic analog: 6-norherboxidiene.

We investigated whether QoL varies between women with and without severe primary dysmenorrhea, and whether QoL is impaired only during menstruation or also during pain-free phases of the menstrual cycle.

An HPLC method for the assay of the heat shock protein 90 inhibitor, PU-H71 (NSC 750424), has been developed and validated.

Tumor glycomics research in recent years has uncovered a large panel of tumor-associated carbohydrate antigens and evidence of immune recognition of tumor-derived aberrant carbohydrates.

Here, we identify gaps in which computational approaches have been used for some neglected diseases and not others. We also make recommendations for the broad-spectrum integration of these techniques into…

This review focuses on the method developments in obtaining biologically active NC1 domains and for specific evaluations in different scenarios.

On the occasion of the second anniversary of the Fukushima disaster, it was reported inScience magazine that evacuees were still waiting to go home, but fortunately that radionuclide exposure, at…

We investigated memory performance and cardiovascular activity in 13 primary insomniacs (PI) compared to 13 good sleepers (GS).