Biomedical sciences publications
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Ancient origin and conserved gene function in terpene pheromone and defense evolution of stink bugs and hemipteran insects
The origin of enzymes involved in terpene biosynthesis and their evolution in insect genomes is still poorly understood. We addressed this question by investigating the evolution of isoprenyl diphosphate synthase…
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Social Epidemiology of Early Adolescent Cyberbullying in the United States
Our objective was to determine the prevalence and sociodemographic correlates of cyberbullying victimization and perpetration among a diverse population-based sample of adolescents.
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Wearable and mobile technology to characterize daily patterns of sleep, stress, presleep worry, and mood in adolescent insomnia
There is a bidirectional relationship between daily stress and sleep, with daily stress negatively impacting sleep, which in turn leads to more stress in adolescents with and without insomnia symptoms.
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The development of sleep/wake disruption and cataplexy as hypocretin/orexin neurons degenerate in male vs. female Orexin/tTA; TetO-DTA Mice
We compared the development of narcoleptic symptomatology in male vs. female orexin-tTA; TetO-DTA mice, a model in which Hcrt neuron degeneration can be initiated by removal of doxycycline (DOX) from…
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Screen Time and Obsessive-Compulsive Disorder Among Children 9–10 Years Old: A Prospective Cohort Study
The aim of this study is to determine the prospective associations between baseline screen time and obsessive-compulsive disorder (OCD) at 2-year follow-up in a national (United States) cohort of 9-…
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The role of ovarian hormones in the pathophysiology of perimenopausal sleep disturbances: A systematic review
We reviewed the literature about the influence of ovarian hormones on sleep in perimenopausal women, summarize the potential underlying pathophysiology of menopausal sleep disturbances and evaluate the implications of these…
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Cyberbullying and Sleep Disturbance Among Early Adolescents in the U.S
We analyzed cross-sectional data from the Adolescent Brain Cognitive Development (ABCD) Study and examined the association between cyberbullying and self-reported and caregiver-reported sleep disturbance measures.
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Lower daily steps among U.S. adolescents during the COVID-19 pandemic: Objective findings from the Adolescent Brain Cognitive Development Study
Keywords: ABCD, Adolescent Brain and Cognitive Development; Adolescent; Covid-19; Fitbit; Pandemic; Physical activity; Steps
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Recommendations for Identifying Valid Wear for Consumer-Level Wrist-Worn Activity Trackers and Acceptability of Extended Device Deployment in Children
The aim of this study was to determine acceptability of Fitbit Charge HR for children and their families, and to determine best practices for processing its objective data.
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Adverse childhood experiences and early adolescent cyberbullying in the United States
This study aimed to determine the associations between adverse childhood experiences (ACEs) and cyberbullying victimization among a diverse sample of early adolescents.
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The “Janus-like” RNA-editing machinery in innate antiviral immunity
We discuss ideas and tools to identify the orphan drug candidates, including small molecules and biologics that may serve as effective modulators of the ADAR-1/IFN innate immunity and are thereby…
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Electrically regulated cell-based intervention for viral infections
This work reports on an engineered cell that—when electrically stimulated—synthesizes a desired protein, that is, ES-Biofactory.