Biomedical sciences publications
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Visual Search and the Aging Brain: Discerning the Effects of Age-Related Brain Volume Shrinkage on Alertness, Feature Binding, and Attentional Control
Poorer conjunction, but not feature, search performance was related to older age and volume shrinkage of nodes in the dorsolateral processing stream.
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Cytotoxic Monacolin Analogs from Monascus Purpureus-Fermented Rice
Two new monacolin analogs, monacolins O (1) and P (2), along with three known analogs, have been isolated from the ethanolic extract of Monascus purpureus-fermented rice.
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Incorrect ICBM-DTI-81 Atlas Orientation and White Matter Labels
Unfortunately, in our work using this atlas, we have encountered several substantial problems in terms of (a) correctness of spatial orientation and (b) correctness of white matter tract labels.
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Characterization of a Diffusible Signaling Factor from Xylella Fastidiosa
We describe here the isolation and characterization of an X. fastidiosa DSF (XfDSF) as 2(Z)-tetradecenoic acid. This compound was isolated both from recombinant Erwinia herbicola expressing X. fastidiosa rpfF and…
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The Tissint Martian Meteorite as Evidence for the Largest Impact Excavation
Here we show that the Tissint meteorite, a 2011 meteorite fall, contains virtually all the high-pressure phases (seven minerals and two mineral glasses) that have been reported in isolated occurrences…
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A Mechanism of Rapidly Reversible Cerebral Ventricular Enlargement Independent of Tissue Atrophy
Here, multimodal imaging, incorporating structural MRI, MRS, and DWI, was used in rats exposed to binge ethanol to provide insight into a mechanism of reversible ventricular enlargement.
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Understanding the Sleep-Wake Cycle: Sleep, Insomnia, and the Orexin System
Andrew D. Krystal, MD, MS, gathered a panel of experts in the area of the sleep-wake cycle and insomnia to review recent research and advances in understanding, current treatments for…
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Remapping the Brain to Compensate for Impairment in Recovering Alcoholics
We tested whether previously published functional magnetic resonance imaging data acquired in 15 recovering alcoholics and 15 controls at rest and while performing a spatial working memory task would fulfill…
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Catalytic Detoxification of Nerve Agent and Pesticide Organophosphates by Butyrylcholinesterase Assisted with Non-Pyridinium Oximes
In the present paper we show a comprehensive study on hydrolytic detoxification of nerve agent and pesticide OPs catalysed by purified hBChE in combination with novel non-pyridinium oxime reactivators.
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Targeting Glioblastoma Stem Cells: Cell Surface Markers
In this review, we primarily summarize recent advances in identification of GSC markers, with a particular focus on cell surface markers.
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Gender-Stratified Gene and Gene-Treatment Interactions in Smoking Cessation
We conducted gender-stratified analyses on a systems-based candidate gene study of regions involved in nicotinic response and the brain—reward pathway in two randomized clinical trials of smoking cessation treatments (placebo,…
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The DRD4 Exon III VNTR, Bupropion, and Associations with Prospective Abstinence
We used univariate, multivariate, and longitudinal logistic regression to evaluate effects on point prevalence and continuous abstinence at end of treatment in European ancestry participants in a trial randomizing participants…