Biomedical sciences publications
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Synthesis of 3H-Labeled Tetrabenazine (TBZ)
Our method provides tritium-labeled TBZ with high specific activity and radiochemical purity, which allow the further investigation of a TBZ in the neurological field.
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Multiple Gap-Filling of Flux-Balance Models
Keywords: Artificial Intelligence, Artificial Intelligence Center, AIC
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Substrate Specifity Profiling of the Aspergillus Fumigatus Proteolytic Secretome Reveals Consensus Motifs with Predominance of Ile/Leu and Phe/Tyr
This report provides proof-of-principle for the use of protease substrate specificity profiling to define the proteolytic secretome of Aspergillus fumigatus.
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Iron-Ion Radiation Accelerates Atherosclerosis in Apolipoprotein E-Deficient Mice
Recently, concern over whether exposure to cosmic radiation might pose a similar risk for astronauts has increased. To address this question, we examined the effect of 2 to 5 Gy iron…
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Epstein-Barr Virus Micrornas and Lung Cancer
We conducted the first analysis of viral microRNAs (miRNAs) in lung cancer, with a focus on Epstein–Barr virus (EBV).
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Absence of Association Between Specific Common Variants of the Obesity-Related Fto Gene and Psychological and Behavioral Eating Disorder Phenotypes
To determine whether FTO may influence weight regulation through psychological and behavioral factors, seven single-nucleotide polymorphisms of the FTO gene were genotyped in individuals with anorexia nervosa (AN) and 677…
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Disruption of Emotion and Conflict Processing in HIV Infection with and Without Alcoholism Comorbidity
We investigated whether patients with alcoholism, HIV-1 infection, or both diseases have greater difficulty than healthy controls in resolving conflict from emotional words with different valences.
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Acylideneoxoindoles: A New Class of Reversible Inhibitors of Human Transglutaminase 2
Inhibitors of human transglutaminase 2 (TG2) are anticipated to be useful in the therapy of a variety of diseases including celiac sprue as well as certain CNS disorders and cancers.
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Dynamic and High-Resolution Metabolic Imaging of Hyperpolarized [1- 13C]-Pyruvate in the Rat Brain Using a High-Performance Gradient Insert
Here a high-performance gradient insert was used in combination with undersampled spiral CSI to increase either the imaging speed or the spatial resolution of hyperpolarized 13C metabolic imaging on a clinical…
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The Human Epithelial Carcinoma Antigen Recognized By Monoclonal Antibody Ae3 Is Expressed on a Sulfoglycolipid in Addition to Neoplastic Mucins
We have carried out carbohydrate microarray analyses of one of the monoclonal antibodies, AE3, that has been regarded the ‘most carcinoma specific’ in respect to its ability to detect HCA…
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Detection of Inflammatory Arthritis By Using Hyperpolarized 13 C-Pyruvate with Mr Imaging and Spectroscopy
The data presented herein suggest that the presence of inflammation may be detected at 13C-MR spectroscopy as the increased conversion of hyperpolarized 13C-pyruvate into 13C-lactate.
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Genetic Variability of Smoking Persistence in African Americans
We undertook an association analysis by using a genotyping array that includes 2,100 genes to analyze smoking persistence in unrelated African American participants from the Atherosclerosis Risk in Communities study.