Biomedical sciences publications

Genome-wide association studies have linked single-nucleotide polymorphisms (SNPs) in the CHRNA5/A3/B4 gene cluster with heaviness of smoking.

We designed and conducted the first-ever phase 0 chemoprevention trial to evaluate and compare the effects of food and formulation on SR13668 bioavailability.

This paper describes such a Melanoma Molecular Disease Model reflecting the latest scientific, clinical, and technological advances.

We examined DMN functional connectivity using functional magnetic resonance imaging (fMRI) data and graph theory analysis.

We used mutational analysis, monitored by CD and NMR, and functional assays to determine the role of this buried salt bridge.

We assessed the sensitivity to SHSe using reactions commonly used for the assessment of sensitivity to the first-smoked cigarette, and investigated the factor structure of these reactions for the purpose…

We report that PGRN bound directly to tumor necrosis factor receptors (TNFRs) and disturbed the TNFα-TNFR interaction. PGRN-deficient mice were susceptible to collagen-induced arthritis, and administration of PGRN reversed inflammatory…

We tested the hypothesis that N/OFQ modulates the SIA directly via the inhibition of the Hcrt neurons in the lateral hypothalamus.

This issue’s special section on “Sleep through the Ages” contains papers addressing the neurological and neuropsychological implications of sleep in adolescents, older adults and insomnia sufferers, highlighting relations of sleep…

An experimental and modeling program has been performed at Sandia National Laboratories to better characterize the effectiveness of barrier walls to reduce hazards. This paper describes the experimental and modeling…

Experiments were conducted to determine whether the β2-AR agonist (R,R′)-fenoterol and other β2-AR agonists could attenuate mitogenesis and, if so, by what mechanism.

This study aims to evaluate the effect of alcoholism and age on δ and θ oscillations and the relationship between these oscillations and measures of white matter microstructural integrity.