Biomedical sciences publications
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Molecular and Anatomical Signatures of Sleep Deprivation in the Mouse Brain
Using a systematic immediate-early gene (IEG) mapping to detect neuronal activation, the consequences of SD were mapped primarily to forebrain regions.
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Cerebral Dynamics and Metabolism of Hyperpolarized 1- 13 Cpyruvate Using Time-Resolved Mr Spectroscopic Imaging
Dynamic hyperpolarized [1-13C]pyruvate metabolic imaging in the normal anesthetized rat brain is demonstrated on a clinical 3-T magnetic resonance imaging scanner.
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Contribution of Callosal Connections to the Interhemispheric Integration of Visuomotor and Cognitive Processes
The reviewed studies on patients with callosal degradation with and without disconnection indicate a dissociation of callosal functions.
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Combining Structure and Appearance Cues for Real-Time Pedestrian Detection
We present a real-time pedestrian detection system which uses cues derived from structure and appearance classification.
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Longitudinal Study of Callosal Microstructure in the Normal Adult Aging Brain Using Quantitative DTI Fiber Tracking
We present a review of neuroimaging studies of normal adult aging conducted with diffusion tensor imaging (DTI) and data from one of the first longitudinal studies using DTI to study…
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The Right Formulation – and How to Get There
This article by Gita Shankar, PhD, Director of Formulations R&D, Pharmaceutical Sciences at SRI, describes the strategy that the company uses to develop an appropriate formulation.
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Transcallosal White Matter Degradation Detected with Quantitative Fiber Tracking in Alcoholic Men and Women: Selective Relations to Dissociable Functions
Here, we examined six anatomically defined transcallosal white matter fiber bundles and asked whether any bundle was specifically vulnerable to alcohol, what aspect of white matter integrity was most affected,…
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Incident Sleep Disordered Breathing in Old Age
We prospectively examined elderly volunteers to understand how changes in body weight are related to SDB for a period of 20–30 years.
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The SRI24 Multichannel Atlas of Normal Adult Human Brain Structure
This article describes the SRI24 atlas, a new standard reference system that was created using template-free population registration of high-resolution magnetic resonance images.
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Erratum: Genome-Wide Association for Smoking Cessation Success: Participants in the Patch in Practice Trial of Nicotine Replacement (Pharmacogenomics (2010) 11:3 (357-367))
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Sleep Evoked Delta Frequency Responses Show a Linear Decline in Amplitude Across the Adult Lifespan
The present study describes data from 70 normal healthy men and women. K-Complexes were evoked using short auditory tones and recorded from a midline array of scalp sites.
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Utility of Digital Stereo Images for Optic Disc Evaluation
Purpose.: To assess the suitability of digital stereo images for optic disc evaluations in glaucoma.