Biomedical sciences publications
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Hibernation
In fact, as argued here, it is likely that opportunistic heterotherms may be better equipped to deal with the challenges of anthropogenic influences than homeotherms because heterotherms have highly flexible…
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Phase I Metabolic Genes and Risk of Lung Cancer: Multiple Polymorphisms and mRNA Expression
We analyzed 25 SNPs (single nucleotide polymorphisms) in 2101 primary lung cancer cases and 2120 population controls from the Environment And Genetics in Lung cancer Etiology (EAGLE) study.
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Meeting Report: Consensus Statement – Parkinson’s Disease and the Environment: Collaborativeon Health and the Environment and Parkinson’s Action Network (CHE PAN) Conference 26-28 June 2007
In June 2007, a multidisciplinary group of experts gathered in Sunnyvale, California, USA, to assess what is known about the contribution of environmental factors to PD.
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SLC6A3 and Body Mass Index in the Prostate, Lung, Colorectal and Ovarian Cancer Screening Trial
We evaluated associations between polymorphisms at the dopamine transporter gene(SLC6A3) and body mass index (BMI), among participants in the Prostate, Lung, Colorectal and Ovarian (PLCO) Cancer Screening Trial.
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Interference Between Modalities as a Measure of Processing Inefficiency in Alcoholics
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Multiple Distinct Risk Loci for Nicotine Dependence Identified By Dense Coverage of the Complete Family of Nicotinic Receptor Subunit (CHRN) Genes
We analyzed 226 SNPs covering the complete family of 16 CHRN genes, which encode the nicotinic acetylcholine receptor (nAChR) subunits, in a sample of 1,050 nicotine-dependent cases and 879 non-dependent controls of…
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Self-Reported Sleep Habits in Middle School Girls: the Girls’ Middle School Longitudinal Sleep Survey
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Choline Acetyltransferase Expression During Spontaneous Sleep-Wake Bouts Over 24H
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Therapeutic Efficacy of a Melatonin Agonist, Ramelteon, and a Benzodiazepine, Triazolam, in a Mouse Genetic Model of Advanced Sleep Phase Syndrome
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Enhanced Alpha-Synuclein Expression in Human Neurodegenerative Diseases: Pathogenetic and Therapeutic Implications
Here we discuss the possibility that other mechanisms of alpha-synuclein elevation contribute to the pathogenesis of idiopathic, sporadic Parkinson's disease and other human synucleinopathies.
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Expression of Plasticity-Related Genes During Eszopiclone-Induced Sleep
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Nociceptin/Orphanin FQ Antagonists Ameliorate the Disease Pathogenesis During Inflammatory Bowel Disease
We evaluated the therapeutic potential of N/OFQ antagonists in C57Bl/6 mice in an IBD model after disease induction by treatment for 5 days with DSS, and subsequent observation of the…