Biomedical sciences publications
-
A Pilot Evaluation of a Nasal Expiratory Resistance Device for the Treatment of Obstructive Sleep Apnea
The present pilot study tests the hypothesis that the application of expiratory resistance via a nasal valve device would improve breathing during sleep in subjects with OSA and in primary…
-
Variants in Nicotinic Receptors and Risk for Nicotine Dependence
The purpose of this study was to replicate these findings in an independent data set and more thoroughly investigate the role of genetic variation in the cluster of physically linked…
-
Translational Studies of Alcoholism: Bridging the Gap
Together, studies in humans and animal models have provided support for the involvement of specific brain structures over the course of alcohol addiction.
-
Mast Cell-Expressed Orphan Receptor Ccrl2 Binds Chemerin and Is Required for Optimal Induction of Ige-Mediated Passive Cutaneous Anaphylaxis
We show that the mast cell–expressed orphan serpentine receptor mCCRL2 is not required for expression of IgE-mediated mast cell–dependent passive cutaneous anaphylaxis but can enhance the tissue swelling and leukocyte…
-
Comparison of Filling Agents for Lip Augmentation
The authors discuss various filling agents currently available that can be used to augment the lips, correct perioral rhytides, and enhance overall lip appearance.
-
The Influence of Reproductive Status and Age on Women’s Sleep
This review paper summarizes presentations from a conference update on the state of knowledge about the extent to which reproductive status and age influence women's sleep.
-
Gene Expression Analysis Reveals New Possible Mechanism of Vancomycin-Induced Nephrotoxicity and Identifies Gene Markers Candidates
The goals of this study were to gain insights into molecular mechanisms of nephrotoxicity at the genomic level, evaluate gene markers of vancomycin-induced kidney injury, and compare gene expression responses…
-
Genome-Wide Linkage of Cotinine Pharmacokinetics Suggests Candidate Regionson Chromosomes 9 and 11
We conducted a whole-genome linkage analysis to search for candidate regions influencing quantitative variation in cotinine pharmacokinetics in a large-scale pharmacokinetic study with 61 families containing 224 healthy adult participants.
-
Comparing Two Strains of Rats in the Chronic Construction Injury Model of Neuropathic Pain
-
Genetic Influences in the Variation in Renal Clearance of Nicotine and Cotinine
In this study of 139 pairs of twins, we have estimated the genetic and environmental contributions to total renal clearance and net secretory/ reabsorptive clearance of nicotine and cotinine.
-
Detoxification of Molinate Sulfoxide: Comparison of Spontaneous and Enzmatic Glutathione Conjugation Using Human and Rat Liver Cytosol
This study compared the metabolic capability of rat and human liver cytosol to form a glutathione (GSH)-conjugated metabolite of molinate.
-
17 Alpha-Estradiol: a Less-Feminizing Estrogen
A substantial number of studies report that 17β-estradiol (E2; estrogen), a potent endogenous feminizing hormone, is neuroprotective.