Biomedical sciences publications

We show here that hexanoic acid, heptanoic acid, octanoic acid, nonanoic acid, decanoic acid, ethylhexanoate, and methyloctanoate decrease intracellular inositol levels and increase the expression of INO1, the gene encoding myo-inositol-3-phosphate synthase…

The present pilot study tests the hypothesis that the application of expiratory resistance via a nasal valve device would improve breathing during sleep in subjects with OSA and in primary…

Together, studies in humans and animal models have provided support for the involvement of specific brain structures over the course of alcohol addiction.

We show that the mast cell–expressed orphan serpentine receptor mCCRL2 is not required for expression of IgE-mediated mast cell–dependent passive cutaneous anaphylaxis but can enhance the tissue swelling and leukocyte…

The authors discuss various filling agents currently available that can be used to augment the lips, correct perioral rhytides, and enhance overall lip appearance.

This review paper summarizes presentations from a conference update on the state of knowledge about the extent to which reproductive status and age influence women's sleep.

The goals of this study were to gain insights into molecular mechanisms of nephrotoxicity at the genomic level, evaluate gene markers of vancomycin-induced kidney injury, and compare gene expression responses…

We conducted a whole-genome linkage analysis to search for candidate regions influencing quantitative variation in cotinine pharmacokinetics in a large-scale pharmacokinetic study with 61 families containing 224 healthy adult participants.

The objective of this study was to examine whether daytime sleepiness assessed using the Epworth Sleepiness Scale and depressive symptoms assessed using the Geriatric Depression Scale are genetically related.

In this study of 139 pairs of twins, we have estimated the genetic and environmental contributions to total renal clearance and net secretory/ reabsorptive clearance of nicotine and cotinine.

This study compared the metabolic capability of rat and human liver cytosol to form a glutathione (GSH)-conjugated metabolite of molinate.