Biomedical sciences publications
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Optical Scanner for Immunoassays with Up-Converting Phosphorescent Labels
Our results suggest that a simple 2-D imaging system can speed assay development, reduce errors, and improve accuracy by characterizing the spatial distribution and uniformity of surface-captured optical labels as…
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In vivo Identification of Novel STAT5 Target Genes
To better characterize the differential contribution of STAT5A and STAT5B in gene regulation, we performed single or double knockdown of STAT5A and STAT5B using small interfering RNA. Subsequent gene expression…
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American Institute of Ultrasound in Medicine Consensus Report on Potential Bioeffects of Diagnostic Ultrasound: Executive Summary
The following summary is not meant as a substitute for the detailed examination of issues presented in each of the articles but rather as a means to facilitate further study…
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The SRI24 Multi-Channel Brain Atlas: Construction and Applications
We present a new standard atlas of the human brain based on magnetic resonance images. The atlas was generated using unbiased population registration from high-resolution images obtained by multichannel-coil acquisition…
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Effect of Chitosans and Other Excipientson the Permeation of Ketotifen, FITC-Dextran, and Rhodamine 123 Through Caco-2 Cells
Ketotifen, FITC-labeled dextran, and Rhodamine 123 permeation was evaluated across Caco-2 cells grown on permeable inserts in the presence of chitosan, N,O-carboxymethyl chitosan (NOCC), Carbopol 934P, Polysorbate 80, and Disodium…
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Fast Parallel Spiral Chemical Shift Imaging at 3T Using Iterative Sense Reconstruction
Spiral chemical shift imaging (CSI) is a fast CSI technique that speeds up the data acquisition in comparison to conventional phase-encoded CSI by sampling the data while oscillating gradients are…
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Children of Persons with Alzheimer Disease: What Does the Future Hold?
Children of persons with Alzheimer disease (AD), as a group, face an increased risk of developing AD.
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Metallothionein Induction By Hypoxia Involves Cooperative Interactions Between Metal-Responsive Transcription Factor-1 and Hypoxia-Inducible Transcription Factor-1 Alpha
Here, we provide evidence that the protumorigenic hypoxia-inducible transcription factor-1α (HIF-1α) is essential for induction of MT-1 by hypoxia, but not zinc.
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Sleep and Menstrual-Related Disorders
There are few studies of sleep in menstrual-related disorders. Preliminary evidence indicates subtle differences in sleep and circadian regulation in women with severe premenstrual syndrome, and increased subjective sleepiness in…
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Cortical Processing of Respiratory Afferent Stimuli During Sleep in Children with the Obstructive Sleep Apnea Syndrome
Cortical processing of respiratory afferent information can be tested by measuring respiratory-related evoked potentials (RREPs). We hypothesized that children with OSAS have blunted RREP responses compared to normal children during…
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Roles of Insulin and Transferrin in Neural Progenitor Survival and Proliferation
In the current study, we examined the requirements for NSC proliferation and survival in vitro using the neurosphere culture system.
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Frontal Callosal Fiber Integrity Selectively Predicts Coordinated Psychomotor Performance in Chronic Alcoholism
Quantitative fiber tracking with diffusion tensor imaging (DTI) provides a new approach for assessing deficits in the microstructural integrity of white matter circuits that may underlie cognitive deficits associated with…