Publications
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Total Exposure Study Analysis Consortium: A Cross-Sectional Study of Tobacco Exposures
The Total Exposure Study was designed to estimate levels of biomarkers of tobacco-specific and non-specific exposure and of potential harm in U.S. adult current cigarette smokers and tobacco product non-users.
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Pathophysiology of L-dopa-induced motor and non-motor complications in Parkinson’s disease
The present review attempts to provide an overview of our current understanding of dyskinesia and other L-dopa-induced dysfunctions, a field that dramatically evolved in the past twenty years.
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Start Making! @ Clubhouses – Final Evaluation Report
The report includes an overview of the program implementation at participating Clubhouses and a summary of evidence of outcomes for participants and organizations aligned to each of the program goals.
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Speech-based assessment of PTSD in a military population using diverse feature classes
We analyzed recordings of the Clinician-Administered PTSD Scale (CAPS) interview from military personnel diagnosed as PTSD positive versus negative.
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Prediction of heart rate changes from speech features during interaction with a misbehaving dialog system
This study examines two questions: how do undesirable system responses affect people physiologically, and to what extent can we predict physiological changes from the speech signal alone?
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Evaluation of Rocketship Students’ Middle School Outcomes: Key Findings from First-Year Interim Report
This document summarizes the findings from the first year of the evaluation. SRI’s final report is expected in Summer 2016 and will include further analyses of student achievement outcomes and…
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Human endogenous retrovirus K and cancer: Innocent bystander or tumorigenic accomplice?
This review will summarize the current state of knowledge regarding HERV-K and cancer and attempt to outline the potential mechanisms by which HERV-K could be involved in the onset and…
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SR-2P vaginal microbicide gel provides protection against herpes simplex virus 2 when administered as a combined prophylactic and postexposure therapeutic
Here, we show that a dose of SR-2P administered 24 h prior to infection provides some protection against the virus, but to a lesser degree than SR-2P administered either once…
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Mitigating the effects of non-stationary unseen noises on language recognition performance
We introduce a new dataset for the study of the effect of highly non-stationary noises on language recognition (LR) performance.
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The spliceosome is a therapeutic vulnerability in MYC-driven cancer
Here we discover that the spliceosome is a new target of oncogenic stress in MYC-driven cancers. We identify BUD31 as a MYC-synthetic lethal gene in human mammary epithelial cells, and…
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The splicing modulator sudemycin induces a specific antitumor response and cooperates with ibrutinib in chronic lymphocytic leukemia.
We report that the spliceosome modulator sudemycin induces selective cytotoxicity in primary chronic lymphocytic leukemia (CLL) cells when compared with healthy lymphocytes and tumor cells from other B-lymphoid malignancies, with…
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Sustainment of model demonstration projects: Findings from follow-up studies
This brief was developed as part of the Model Demonstration Coordination Center (MDCC) operated by SRI International for the U.S. Department of Education, Office of Special Education Programs.