BIOSCIENCES
Next-generation drugs, diagnostics, and technologies to solve urgent medical needs
We develop transformative approaches and platforms for challenging therapeutic problems. We conduct basic and translational research, have the breadth — and depth — to deliver the latest in biomedical research through technology development. Our researchers have a rich legacy of collaboration with government agencies and industry partners that improve health outcomes and well-being around the world. Our projects range from high-impact, early-stage research to drug co-development with pharmaceutical and biotech companies. Contact us to learn more.
200+Research and technical staff(40% PhDs)
200+Biomedical products moved to clinical trials
11Partnerships with National Institutes of Health Divisions
“Because we’re a nonprofit with a mission to make the world a better place, there’s a lot of flexibility in the types of projects we can pursue. We can do earlier stage research that may have higher impact without as much emphasis on the bottom line. And when we collaborate with pharmaceutical companies, it’s truly a co-development process — sharing expertise and innovating together.”
Kathlynn Brown, PhDPresident – Biosciences Division
New ways of thinking about human health
Uncommon in the world of tech development, SRI Biosciences brings together basic bioscience, applied research for early-stage IP generation, and translational development — moving the lab to the real world.
Real-world impact
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The naked mole rat may hold the key to new treatments for neurodegenerative diseases
SRI researchers study the cells of the long-living rodent to find new drug targets for Alzheimer’s, Parkinson’s, and other neurodegenerative disorders.
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Engineered helper T cell could become a cancer killer
SRI scientists are developing a cell-based platform using an often-undervalued subset of helper T cells to deliver potent antitumor proteins for solid tumors, overcoming dose-related toxicities.
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SRI identifies predictors of adolescent obesity
As part of a nationwide longitudinal study of adolescent brain development, researchers use AI to analyze data to pinpoint obesity risk factors.
Recent publications
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Deficiency of orexin signaling during sleep is involved in abnormal REM sleep architecture in narcolepsy
Here, we determined the activity dynamics of orexin neurons during sleep that suppress the abnormal REM sleep architecture of narcolepsy.
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Identification and characterization of screen use trajectories from late childhood to adolescence in a US-population based cohort study
This study will identify and characterize the subgroups of adolescents sharing similar trajectories of screen use from childhood to adolescence.
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Biological sex influences sleep phenotype in mice experiencing spontaneous opioid withdrawal
We describe here a model of opioid withdrawal in mice that resembles the sleep phenotype characteristic of withdrawal in humans.